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| MATERIAL SAFETY DATA SHEET |
| Manufacturer: | JEMA Biosciences P. O. Box 635193 San Diego, CA 92163-5193, U.S.A. www.jemabiosciences.com |
| SECTION 1: Product Identification | |
|---|---|
| Chemical Name: | BSH, Bacillithiol ,2-[[2-[[(2R)-2-amino-3-mercapto-1-oxopropyl]amino]-2-deoxy-α-D-glucopyranosyl]oxy]-(2S)-butanedioic acid |
| Note: | Material is provided as its trifluoracetic acid salt |
| Product Number: | 11-001 |
| CAS Registry Number: | 1184928-91-3 |
| Formula: | C15H23F3N2O12S |
| Purity: | 98% |
| Chemical Family: | redox thiol |
| SECTION 2: Composition and Information on Ingredients | |
|---|---|
| Ingredient: | Bacillithiol trifluoroacetic acid salt |
| CAS Number: | 1184928-91-3 |
| Percent: | 100% |
| ACGIH (TWA): | 2.5mg/m3 (as F) |
| OSHA (PEL): | 2.5mg/m3 (as F) |
| H-statement (GSSH): | none |
| R-statement: | none |
| SECTION 3: Hazards Identification | |
|---|---|
| Emergency Overview: | BSH is sold in small quantities and when used as such does not present considerable health risks. |
| Primary Routes of Exposure: | None |
| Eye Contact: | None |
| Skin Contact: | None |
| Inhalation: | May be to the nose, mucous membranes and respiratory tract. |
| Ingestion: | No information available on the physiological effects of ingestion. May be harmful if swallowed. |
| Acute Health Effects: | Irritating to skin, eyes and respiratory tract. |
| Chronic Health Effects: | None |
| NTP: | No |
| IARC: | No |
| OSHA: | No |
| SECTION 4: First Aid Measures | |
|---|---|
| Eye Exposure: | Immediately flush the eyes with copious amounts of water for at least 15 minutes. A victim may need assistance in keeping their eye lids open. Get immediate medical attention. |
| Skin Exposure: | Wash the affected area with water. Remove contaminated clothes if necessary. Seek medical assistance if irritation persists. |
| Inhalation: | Remove the victim to fresh air. Closely monitor the victim for signs of respiratory problems, such as difficulty in breathing, coughing, wheezing, or pain. In such cases seek immediate medical assistance. |
| Ingestion: | Seek medical attention immediately. Keep the victim calm. Give the victim water (only if conscious). Induce vomiting only if directed by medical personnel. |
| SECTION 5: Fire Fighting Measures | |
|---|---|
| Flash Point: | no data |
| Autoignition Temperature: | no data |
| Explosion Limits: | no data |
| Extinguishing Medium: | non flammable |
| Special Fire Fighting Procedures: | no special procedures when working with milligram quantities of this material |
| Hazardous Combustion and Decomposion Products: | no data |
| Unusual Fire or Explosion Hazards: | No unusual fire or explosion hazards. |
| SECTION 6: Accidental Release Measures | |
|---|---|
| Spill and Leak Procedures: | Small spills can be mixed with vermiculite or sodium carbonate and swept up. |
| SECTION 7: Handling and Storage | |
|---|---|
| Handling and Storage: | Store under argon or nitrogen atmosphere at -20 °C |
SECTION 8: Exposure Controls and Personal Protection |
|
|---|---|
| Eye Protection: | Always wear approved safety glasses when handling a chemical substance in the laboratory. |
| Skin Protection: | Wear protective clothing and gloves. |
| Ventilation: | Not required. |
| Respirator: | Not required. |
| Additional Protection: | No additional protection required. |
| SECTION 9: Physical and Chemical Properties | |
|---|---|
| Color and Form: | colorless oil |
| Molecular Weight: | 512.08 |
| Melting Point: | no data |
| Boiling Point: | no data |
| Vapor Pressure: | no data |
| Specific Gravity: | no data |
| Odor: | none |
| Solubility in Water: | soluble |
| SECTION 10: Stability and Reactivity | |
|---|---|
| Stability: | oxidation to the corresponding disulfide BSSB occurs at pH > 7 but is slow at pH 2-3 (BSH is stable for weeks when stored at pH 2-3 at -20 °C) |
| Hazardous Polymerization: | no hazardous polymerization |
| Conditions to Avoid: | oxidizing agents, storage at room temperature for extended periods |
| Incompatibility: | oxidizing agents |
| Decomposition Products: | fluorinated by products, N-acetylglycosamine, malic acid, cysteine |
| SECTION 11: Toxicological Information | |
|---|---|
| RTECS Data: | no data |
| Carcinogenic Effects: | no data |
| Mutagenic Effects: | no data |
| Tetratogenic Effects: | no data |
| SECTION 12: Ecological Information | |
|---|---|
| Ecological Information: | No information available |
| SECTION 13: Disposal Considerations | |
|---|---|
| Disposal: | Dispose of according to local, state and federal regulations. |
| SECTION 14: Transportation | |
|---|---|
| Shipping Name (CFR): | Non-hazardous |
| Hazard Class (CFR): | NA |
| Additional Hazard Class (CFR): | NA |
| Packaging Group (CFR): | NA |
| UN ID Number (CFR): | NA |
| Shipping Name (IATA): | Non-hazardous |
| Hazard Class (IATA): | NA |
| Additional Hazard Class (IATA): | NA |
| Packaging Group (IATA): | NA |
| UN ID Number (IATA): | NA |
| SECTION 15: Regulatory Information | |
|---|---|
| TSCA: | Not listed in the TSCA inventory |
| SARA (Title 313): | Not regulated under SARA 313 |
| Second Ingredient: | none |
| Third Ingredient: | none |
| SECTION 16: Other Information | |
|---|---|
| Disclaimer: | The information herein is believed to be accurate and reliable as of the date compiled. JEMA Biosciences makes no warranty, or guarantee of any kind with respect to the information contained in this document or any use of the product based on this information. |
| Preparation Date: | 8/12/2011 |
| Revision Date: | 8/12/2011 |